Equine EPM Support
Equine EPM Support
Equine EPM Support is a focused, whole-systems herbal formulation designed to support horses affected by Equine Protozoal Myeloencephalitis (EPM), as well as horses awaiting diagnostic results. EPM is a neurological condition caused by protozoal organisms that impact the central nervous system, often presenting as incoordination, weakness, muscle asymmetry, or changes in balance and movement.
Rather than approaching EPM as an isolated neurological issue, Wholehearted Harmony addresses it through a systems-based lens, recognizing that immune resilience, nervous system regulation, lymphatic drainage, detoxification, and stress response all play critical roles in a horse’s ability to recover and adapt. Horses with compromised immune systems or chronic systemic stress are often more vulnerable to neurological challenges, making foundational system support essential.
This blend was carefully developed to provide immune modulation, nervous system support, lymphatic movement, and metabolic detoxification while helping the body respond to protozoal stress. The selected herbs work synergistically to support immune signaling, assist the body’s natural clearance processes, protect and nourish nervous tissue, and help regulate stress responses that can exacerbate neurological symptoms.
Rooted in a species-appropriate, forage-first framework, Equine EPM Support is designed to work alongside the horse’s natural biology rather than override it. This formula supports the body’s innate healing mechanisms while respecting the complexity of neurological and immune interactions.
Important Feeding Note:
This blend is no longer offered as a 30-day protocol. Through continued observation and client feedback, we have found that a minimum of 60 days provides more consistent and beneficial support for horses affected by EPM. Horses using this blend preventatively may also benefit from a full 60-day course for optimal systemic support.Equine EPM Support may be used alongside testing protocols and veterinary guidance and is intended to complement, not replace, appropriate diagnostics and care.
Feeding & Use Notes
Designed for a minimum 60-day feeding period
Best used with a forage-based, species-appropriate diet
Feeding amounts are based on the average 1,000 lb horse
Individual needs may vary based on severity, stress level, and overall health
Consultation is encouraged to ensure proper layering or customization.
Note for Professionals
Wholehearted Harmony works with a variety of professionals who support animals and people in their care. If you plan to offer Wholehearted Harmony herbal formulations to your clients, please review our Professional Orders & Packaging Policy by clicking [here].
INGREDIENT PROFILE
All ingredients are 100% Certified Organic or Wildcrafted, Non-GMO, and Kosher.
Equine EPM Support is formulated using cut & sifted herbs to provide targeted neurological and immune support within a whole-systems, species-appropriate framework.
OLIVE LEAF
Targeted Support:
Supports immune response and microbial balance during protozoal stress.
Whole-Systems Support:
Supports immune regulation, inflammatory balance, cardiovascular health, and nervous system protection, helping prevent excessive immune strain.
Nutritional Contribution:
Provides oleuropein, flavonoids, and polyphenols with antioxidant properties that support immune signaling and cellular protection.
PAU D’ARCO
Targeted Support:
Supports the body’s response to protozoal organisms and microbial imbalance.
Whole-Systems Support:
Supports immune resilience, detoxification pathways, and cellular defense mechanisms while assisting the body’s natural regulatory processes.
Nutritional Contribution:
Contains naphthoquinones and antioxidant compounds that support immune function and cellular integrity.
ELEUTHERO
Targeted Support:
Supports immune responsiveness and stress adaptation.
Whole-Systems Support:
Supports adrenal balance, nervous system stability, endurance, and overall resilience during prolonged neurological or immune stress.
Nutritional Contribution:
Provides adaptogenic compounds that support energy metabolism, stress regulation, and immune function.
ASHWAGANDHA
Targeted Support:
Supports nervous system calming and stress modulation.
Whole-Systems Support:
Supports immune balance, adrenal health, neurological resilience, and recovery from chronic stress that can worsen neurological symptoms.
Nutritional Contribution:
Contains withanolides and bioactive compounds that support nervous system health, inflammation regulation, and cellular repair.
CLEAVERS
Targeted Support:
Supports lymphatic drainage and fluid movement.
Whole-Systems Support:
Supports lymphatic circulation, kidney function, nervous system health, and reduction of systemic congestion that can impact neurological signaling.
Nutritional Contribution:
Provides vitamins, minerals, flavonoids, and coumarins that support detoxification and tissue health.
DANDELION ROOT
Targeted Support:
Supports liver function during detoxification and immune activation.
Whole-Systems Support:
Supports metabolic detox pathways, digestive efficiency, immune balance, and clearance of waste products during prolonged immune stress.
Nutritional Contribution:
Rich in vitamins A, B, C, and D, along with iron, potassium, and zinc to support liver function and immune resilience.
ROSEHIPS
Targeted Support:
Supports antioxidant balance and immune resilience.
Whole-Systems Support:
Supports connective tissue health, nervous system protection, immune strength, and recovery from oxidative stress.
Nutritional Contribution:
Exceptionally rich in vitamins C and E, beta-carotene, potassium, calcium, magnesium, and iron.
CALENDULA
Targeted Support:
Supports lymphatic and inflammatory regulation.
Whole-Systems Support:
Supports lymphatic movement, immune balance, tissue repair, and cellular protection while helping soothe systemic inflammation.
Nutritional Contribution:
Provides vitamins A and C along with antioxidant compounds that support immune function and tissue health.
WHY THIS BLEND WORKS
Equine EPM Support addresses neurological health through immune regulation, detoxification, lymphatic movement, stress adaptation, and nervous system nourishment. By supporting targeted physiological needs within a whole-systems, species-appropriate framework, this blend helps the body regulate, adapt, and recover over time when used consistently and appropriately.


Reviews
This is blend that people should consider when you can't quite pin down what might be going on. We have used it on horse who has string halt because of his not so sweet demeanor and it was life changing for him. He is calm and obviously in a lot less discomfort.